Aims Clopidogrel is the most commonly prescribed thienopyridine as part of dual anti-platelet therapy for the treatment of ...

Given that HCQ is metabolized by CYP2C8, CYP2D6, and CYP3A4, the models were applied to simulate the effect of major gene polymorphism on drug disposition. Modeling and simulation were carried out on ...

In fact, the proposed paradigm based on polymorphism, chirality and dangling bonds play a key role in the design of bioactive organic compounds, for instance in industrial applications, where ...

Current evidence shows that genetic variation can determine impaired response to drugs. Polymorphisms can exert an effect on drug action anywhere in the body. Individually, an SNP that alters ...

It’s true to say that drug usage has a variety of negative consequences for its users and, on the whole, governments are right to advise against it. People in New York who smoke cannabis should ...

Weight-loss drugs like Ozempic may decrease your risk of developing 42 health conditions, but increase your chance of experiencing 19 others, according to one of the most comprehensive studies-of ...

Some of China’s senior doctors are raising concern over the quality of domestic generic medicines that have largely replaced western brand-name drugs at hospitals, amid a rare public backlash ...

Blockbuster obesity drugs such as Ozempic have been celebrated for their ability to promote weight loss and treat a surprising range of other conditions, from heart problems to Parkinson’s disease.

Tailoring INH dosage based on NAT2 polymorphism may optimize treatment regimens ... intolerance to first-line anti-tuberculosis drugs, initiation of treatment more than one week before hospital ...