The most popular examples of drugs in this group are aspirin and ibuprofen. NSAIDs may cause some side effects. NSAIDs come under the wider definition of non-opioid analgesics.

Drugs such as dexmedetomidine that bind to the norepinephrine alpha-2a (α 2a) adrenergic receptor are effective analgesics, but their sedative effects limit their widespread use.

The benefits of such over-the-counter pain relievers as aspirin and APCs have long been recognized. But evidence that these familiar remedies are not necessarily harmless in all circumstances has ...

Scientists have investigated a compound called BnOCPA (benzyloxy-cyclopentyladenosine), found to be a potent and selective analgesic which is non-addictive in test model systems. BnOCPA also has a ...

This laboratory model could be used to help explain certain pain syndromes, and offer a new way to test potential analgesic drugs, a Stanford team reports in the journal Nature.

WebMD provides a comprehensive chart of drugs commonly used to treat rheumatoid arthritis, including usage and dosage information, risk factors, and potential side effects.

Pain pathway in a dish could aid search for new analgesic drugs. Jon Hamilton; April 10, 2025 / 3:00 am ... Touch a hot stove, for example, ...

Scientists have recreated a pathway that senses pain, using clusters of human nerve cells grown in a dish.