eLife

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...
EMBO Press

Evolutionary relaxation and functional change of INSL3 and RXFP2 may underlie natural cryptorchidism in mammals

This study examines how evolutionary relaxation and functional change of INSL3 and RXFP2 relate to natural cryptorchidism in ...
eLife

Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System

The authors investigated the epigenetic mechanisms regulating the differentiation of circulating monocytes that infiltrate the CNS and adopt microglia-like characteristics. The work is useful to the ...
BMJ Open

Self-efficacy and influencing factors of returning to work in young and middle-aged patients with aortic dissection in China: a cross-sectional study using latent profile a…

The latent profile analysis was used to identify the self-efficacy groups of young and middle-aged patients with aortic ...
BMJ Open

Maximising the potential of the National Compulsory Service Programme in rural China: a mixed methods study

Objectives To alleviate the shortage of qualified physicians in rural areas, since 2010, the Chinese government has launched a National Compulsory Service Programme (NCSP) to enrol medical students ...