Early seizure onset in DEPDC5-related epilepsy is linked to more severe disease, including drug resistance, intellectual disability, and brain lesions.

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells. This usually happens during fetal ...

Focal cortical dysplasia is caused by areas of the brain that have developed abnormally and is among the most common causes of drug-resistant epilepsy in children. It frequently occurs in the frontal ...

An international consortium has identified at least some of the genetic drivers of a mysterious form of pediatric epilepsy. Epilepsy is present in 4% of the population, and is among the most common ...

To stratify the risk of future epilepsy, physicians have historically used lumbar puncture, neuroimaging, and electroencephalography in these patients. Four predictors of future epilepsy in children ...

An artificial intelligence tool that can detect tiny, hard-to-spot brain malformations in children with epilepsy could help patients access life-changing surgery quicker, Australian researchers said ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...