Polygenic risk scores for Alzheimer’s disease derived from individuals of European ancestry can show improved performance in multiancestry settings after incorporating genome-wide association ...

Disease genetics, of human, animal and plant diseases, investigates the consequences of pathogenic (host) genetic variants as the major causes of heritable disorders (monogenic diseases) as well ...

June 21, 2025 — USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed ...