Hong Qian, Ph.D, professor in Molecular Hematology, a group leader for the research group Leukemia niche [1] at the Center for Hematology and Regenerative Medicine (HERM) at Karolinska Institutet.

An efficient and practical methodology has been developed to introduce the CF3 group onto quinones through Cu(I)-catalyzed direct C–H trifluoromethylation of quinones.

This study presents new mechanistic insights into the frustrated Lewis pairs (FLPs) catalyzed C–H activation of heteroarenes. Besides the generally accepted concerted C–H activation, a novel stepwise ...