How will you create the mouse model? We will use germ-free mice — mice bred with no bacteria in their guts — to trial three methods of recreating the human small-intestinal microbiome in mice.

Gut organoids mimic the stomach, small intestine, and colon in 3D. Learn how these lab-grown models are advancing digestive ...

Pipetting brain organoids at Fides Zenk's laboratory - 2025 EPFL/Zenk Lab Organoids are a promising breakthrough that ...

VivoSim Labs, Inc. (Nasdaq: VIVS) (the “Company” or “VivoSim”) announced today that its NAMkind™ platform for intestinal efficacy prediction was recognized with ...

This was something we also observed in our human studies. This all begs the question: why? Why focus on the small-intestine microbiome? The small intestine is an underexplored microbial organ ...

The stem cells are propagated in vitro and form mature intestinal epithelium upon growth factor manipulation. In order to increase the complexity of this human biomimetic model, we are integrating ...

Study in mice shows how a host-elicited factor benefits gut immunological homeostasis by selectively targeting commensal ceramide molecules.

The human gut is home to trillions of microbes that not only aid in digestion, but also play a key role in shaping our immune ...

but also in a humanized mouse model with cells from PSC patients, which indicates that this effect could also work in the ...

Researchers at Peking University have discovered that a filamentous gut fungus, Fusarium foetens, can reverse metabolic ...

The work describes developing a robust, multicellular in vitro model that closely mirrors human intestinal biology, paving the way for safer and more effective therapies for inflammatory bowel disease ...