Roche will manage antibody selection, conjugation, preclinical and clinical development, and commercialisation. Credit: Melnikov Dmitriy / Shutterstock.com. Roche has signed a new collaboration ...

Matsen et al. describe an approach for training an antibody language model that explicitly tries to remove effects of "neutral mutation" from the language model training task, e.g. learning the codon ...

This fundamental study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides convincing evidence that separating ...