Department of Surgery, Medical University of South Carolina, Charleston, SC. [email protected]. Chronic pancreatitis is best described as a relentless, continuous inflammatory destruction of the ...

Zimislecel is an allogeneic stem cell-derived islet cell therapy that could eliminate the need for insulin in those who have type 1 diabetes. Regulatory submissions are expected in 2026, and if ...

Islet transplantation offers long-term benefits for more than 10 years in reducing diabetes-related complications in patients ...

Vertex is ending work on one of its two clinical-stage islet cell treatments after the diabetes therapy looked unlikely to trigger sufficient levels of insulin production in a phase 1/2 trial.

No severe adverse events associated with the therapy were reported. A novel islet cell therapy delivered through a single infusion lowered HbA1c and eliminated severe hypoglycemia events for all ...

Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been able to come off insulin altogether within a year, raising the prospect of a life without ...

Kyoto University Hospital performed the surgery in February using iPS cell-derived pancreatic islet cells to confirm the safety of the procedure for the autoimmune disease, which prevents the pancreas ...

“Our CB-SCs can target different compartments of the immune system, educating and correcting their dysfunctions at a fundamental level,” says Dr. Zhao. “This therapy has the potential to revolutionize ...

The data were presented as a ratio (annexin-V fluorescence intensity/nuclei fluorescence intensity per islet area). (E) The abundance of apoptotic proteins in transfected Min6 cells was measured ...

In Part B of the study, participants received the full dose of the investigational fully differentiated pancreatic islet cell therapy encapsulated in a proprietary immunoprotective device.