This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

The balance between mitochondrial biogenesis and mitophagy helps maintain a healthy ... are especially vulnerable to reduced oxidative phosphorylation (OxPhos), contributing to cognitive decline.

Many questions remain regarding the regulation of mitoribosome biogenesis and function ... and the translation of OXPHOS proteins slow down. Cells then generate less ATP and keep biological activities ...

This loop refers to the influence of peroxisomal NADH on mitochondrial ATP production, which in turn feeds back to influence peroxisome biogenesis, division, and proliferation. The OXPHOS effect on ...

through the oxidative phosphorylation (OXPHOS) being one of their main functions. Selective elimination of mitochondria by mitophagy, in conjunction with mitochondrial biogenesis, regulates ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Oxidative phosphorylation deficiency causes ...

mitochondrial biogenesis, dynamics and mitophagy in old and sick hearts. This review covers the current knowledge of mitochondrial physiopathology in aging, how disruption of OXPHOS or mitochondrial ...

Mitochondria are then repopulated via PPARGC1A/PGC-1α-mediated biogenesis. Mitochondrial fusion protein OPA1 ... these newly established mitochondrial networks are better primed for OXPHOS and are ...