Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells communicate with one another during this process through cell-surface ...

ACROBiosystems has developed a series of specialized proteases for the screening and validation of ADC linkers, focusing on ...

How do we determine how healthy our food is? We know now that our nutrition shouldn't just be measured in calories, or even ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Given the amino-acid sequence or 3D structure of a protein, ... through the insertion of secondary structure elements 89. Although these might originate from disparate regions of the primary ...

Nanoparticles (NPs) are materials whose dimensions range from 1 to 1,000 nanometers (nm). Due to their nano-scale dimensions and tunable material ...

Secondary structure analysis of the full-length SARS-CoV-2 Nsp1 protein by means of NMR ... In betacoronaviruses, the IDR site (the N protein primary phosphorylation site) that acts as a linker ...

Bottom-up fabrication of self-assembled nanomaterials requires control over forces and interactions between building blocks. We report here on the formation and architecture of supramolecular ...

In this paper, we propose a hybrid RNN/HMM system for protein secondary structure prediction, where each secondary structure segment is approximated by a second-order recurrent neural network embedded ...

The crystal structure of the core domain (N-terminal 30 kDa domain) of cytoskeletal protein 4.1R has been determined and shows a cloverleaf-like architecture. Each lobe of the cloverleaf contains ...

In this study, we focused on the effect of the NP size (curvature) on the protein secondary structure using silica NPs (SiNPs) with diameters of 10 nm, 100 nm, 1 μm, and 10 μm. The secondary structure ...