Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

The study was published under the title "Metabolic rewiring caused by mitochondrial dysfunction promotes mTORC1-dependent skeletal aging" in Science Advances. The researchers undertook a specific ...

Get Instant Summarized Text (Gist) Cells possess a specialized recycling system to repair damaged mitochondrial DNA (mtDNA), which is crucial for preventing diseases like Parkinson's and Alzheimer ...

TMEM65 aids in calcium removal from mitochondria, preventing harmful calcium overload linked to heart failure and Alzheimer's disease. This discovery could lead to new therapeutic strategies ...

In new research published in Nature, scientists have produced the first comprehensive atlas of the tiny energy producers in ...

There’s unexpected movement in the world of cell biology — specifically, with the energy factories known as mitochondria. Ever since they were discovered in the mid-nineteenth century ...

Researchers have identified a molecule that helps more mitochondria function properly. A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic ...

And, for one type of organelle, that principle is now being tested in practice. Mitochondria, the organelles in question, are best known as power packs—places where glucose molecules are ...