Adenylosuccinate lyase (ADSL) deficiency is an inherited metabolic disorder that impairs purine metabolism. ADSL is a key enzyme in both the de novo synthesis and the purine nucleotide cycle ...

Research from all publishers Other recent contributions have further enriched our understanding of nucleotide metabolism. A comprehensive review of purine salvage pathways in plants outlined the ...

China is the world’s largest producer and consumer of meat ducks, with 75% of global duck production. Duck meat occupies an important position in China’s food consumption. (1,2) Skeletal muscle is one ...

The Synthetic Human Genome, or Syn HG, a project launched on June 26th, aims to change that. Funded partly by Wellcome, a ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

BEIJING, June 4, 2025 /PRNewswire/ -- Tsingke Biotech recently participated in TIDES USA 2025, the leading international event for oligonucleotide and peptide therapeutics, held in San Diego from ...

Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the ...