New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for ...

Adenine and guanine are double-ring molecules called purines, but cytosine, thymine, and uracil are all pyrimidines: single rings. To maintain its orderly structure, single rings on one strand can ...

Sequencing DNA from those who lived long ago. Ancient DNA is a new and rapidly growing field, with a Nobel Prize awarded in 2022 to Svante Pääbo for his foundational work.. Using samples taken ...

fraudulent incorporation into DNA and RNA nucleic acids. The first compounds used were structural analogues of purine or pyrimidine bases used in oncology and grouped together under the term ...

While it is unlikely that DNA could be formed in a meteorite, ... Nucleobases belong to classes of organic molecules called purines and pyrimidines, which have a wide variety.

Identifying the wide diversity of extraterrestrial purine and pyrimidine nucleobases in carbonaceous meteorites. Nat Commun 13, 2008; doi: 10.1038/s41467-022-29612-x Published in ...

Delineation of the pathways related with the purine and pyrimidine metabolism in the settings of cancer once again is proving the fact of the intensive DNA syntheses in pathological settings. As any ...

The purine skeleton is a 6-membered pyrimidine ring fused to a 5-membered ... are the recognizable units of RNA and DNA. Therefore, purines are initially formed as ribonucleotides rather ...