New method maps RNA in cells at native locations, revealing spatial responses to signals and offering insight into disease ...

Modeling the structure and dynamics of large macromolecules remains a critical challenge. Molecular dynamics (MD) simulations are expensive because they model every atom independently, and are ...

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Deoxyribonucleic acid (DNA) carries the genetic information needed to sustain life via unique combinations of four different nucleobases (adenine, guanine, thymine, and cytosine) and has a ...

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion.

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

An enzyme type noted in several cancers is the family of adenosine deaminases acting on RNA (ADARs). These enzymes convert ...

Investigations into RNA structure and function in solutions artificially crowded with cosolutes like polyethylene glycol ... and RNA strand separation, is detrimental to the chemical stability of RNA.

New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques.

Using capillary gel electrophoresis, researchers from the National Institute of Health Sciences in Kanagawa, Japan studied the factors that optimize chain-length distribution analysis of messenger RNA ...