Multivalent vaccines with coverage against several filovirus species, rather than multiple monovalent vaccines, are a WHO-stated preferred target product profile characteristic, facilitating ...

We propose that these condensates are replication hubs for human norovirus, an elegant solution to the puzzling question of how ribosome-assisted translation of the viral genome is segregated from its ...

Filoviruses are filamentous, negative-sense RNA viruses, with a genome that encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), matrix protein (VP40), glycoprotein (GP), ...

This discovery could guide the development of universal antiviral therapies targeting multiple filoviruses, enhancing treatment options against Ebola and potentially other related viruses. Key ...

Filovirus Transcription & Replication (Kristina Brauburger, Laure R Deflubé, and Elke Muhlberger) Innate Immune Evasion Mechanisms of Filoviruses (Christopher F Basler, Gaya K Amarasinghe, and Daisy W ...

The use of monoclonal antibodies (mAbs) as therapeutics for filoviral infection has a long and well-vetted history in the filovirus community. Although some of the earliest studies indicated that ...

Background: The Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD). This filovirus first appeared in 1967 and has since caused several outbreaks with case fatality rates ...

AWS offers live replication that also copies metadata, with replication options that can be cross-region, same region, bi-directional, to different storage classes or to different owners, and ...