Groundbreaking First-in-Human Study Establishes Potential to Treat Type 1 Diabetes by Transplanting Insulin-Secreting Cells Without Immunosuppression Six-Month Patient Follow-up Results ...

Vertex Pharmaceuticals may have narrowed its focus this year, but the biopharma’s decision to stick with its remaining islet cell therapy appears to be paying off so far.. The allogeneic human ...

Vadodara: A man from Juna Baria village had a narrow escape on Saturday morning after being stranded for hours on a rocky islet in the middle of a swe.

Islet preparations that had more than 4000 islet equivalents per kilogram of the recipient's body weight in a packed-tissue volume of less than 10 ml were judged safe for transplantation. 16 Each ...

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of ...

Ms. Smith is confident now that those complications won’t be in her future. In February of 2023, she became the first Canadian to receive a transplant of islet cells – the cells in the ...

Findings from two studies reveal advancements in stem cell-derived treatment options to treat type 1 diabetes. Results from the FORWARD study, also simultaneously published in the New England ...

One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 diabetes in whom the benefits outweigh the risks of immunosuppression.

CHICAGO — A single infusion of zimislecel, an investigational stem cell-based therapy, restored physiologic islet function and conferred improved outcomes and insulin independence at 1 year in a ...

High-fat Western diets cause lasting pancreatic damage, impairing insulin release – even after weight loss –highlighting the need for early intervention.

From mixed to matched: new marker pinpoints therapeutically relevant stem cell–derived islets Human pluripotent stem cell–derived islets hold great promise as a functional cure for diabetes.