It's been tough sledding for Ayoka Lee in the Sweet 16 matchup, as the 6-foot-6 center has struggled to counteract USC's two-headed center combo of Marshall and Clarice Akunwafo. Lee has 10 points with three minutes to play but has needed 13 shots to get there.

All No. 1 seeds advanced to the Sweet 16, which tips off Friday. Here’s everything you need to know, including a breakdown of each region.

Last year, there were only four brackets that remained perfect after the first two rounds of the women’s tournament.