A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

Researchers at the University of Illinois Urbana-Champaign have discovered important new clues in the mystery of how an ...

Aspirin-induced ferritin synthesis was abrogated in the presence of the iron chelator desferrioxamine, pointing to an interaction of aspirin with iron-responsive activation of ferritin translation.

Here, the decomposition mechanisms are described for these compounds. In addition to protection against stomach ulceration, these prodrugs exhibited significantly enhanced cytotoxcity compared to ...

The mechanism behind aspirin's anti-cancer effect Aspirin works by inhibiting the production of thromboxane A2 (TXA2), a molecule produced by blood platelets. TXA2, known for its role in blood ...

Their studies did then find that aspirin prevents cancers from spreading by decreasing TXA 2 and releasing T cells from suppression. They used a mouse model of melanoma to show that in animals ...

The traditional mechanisms of low-dose aspirin (e.g. 75 to 100 mg/day) are sufficient to irreversibly acetylate serine 530 of cyclooxygenase (COX)-1, inhibiting platelet generation of thromboxane A2 .

Aspirin was thus unable to prevent migration, invasion, and metastasis in miR-34-deficient cancer cells. It was already known that the miR-34 genes are induced by the transcription factor p53 and ...

Aspirin is one of the most commonly used anti-inflammatory drugs, and it has been around for more than a century. Despite its long history of use, re Monday, 22 May 2023 02:10 GMT ...