A compound best known for giving almonds and apricots their aroma may be the key to defeating hard-to-kill cancer cells. Japanese researchers found that benzaldehyde can stop the shape-shifting ...

A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the ...

The US Food and Drug Administration (FDA) has issued an urgent warning about tianeptine – a substance marketed as a dietary ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

A research team led by Associate Professor Yasushi Segawa, graduate students Mai Nagase (at the time of the research) and Rui Yoshida, and technical staff member Sachiko Nakano of the Institute for ...

When left to chance, both can drift. We often pour immense structure, vision and planning into our companies, yet fail to apply any of those tools at home. That disconnect can be costly.

Abstract: Existing drug discovery pipelines take 5–10 years and cost billions of dollars. Computational approaches aim to sample from regions of the whole molecular and solid-state compounds called ...

Water plays a crucial role in determining the functions of biomolecules and nanomaterials. However, the electronic structure of water molecules at the nanoscale remains elusive. In this study, we ...

Efficient catalytic CO2 conversion by harnessing visible-light energy is a substantial challenge for sustainability. Photocatalytic materials consisting of light absorbers and catalysts have been ...

The model’s predecessor, Boltz-1, was released last November as the first fully open-source model to achieve AlphaFold 3-level accuracy in predicting the 3D structure of biomolecular complexes ...

Scientists have discovered that a molecule known for defending animal immune systems called itaconate also plays a powerful role in plants. Researchers showed that itaconate not only exists in ...