The cell membrane is the cell's outermost line of defense against SARS-CoV-2, the novel coronavirus responsible for COVID-19 disease.

Virus membrane-fusion proteins drive the fusion reaction by undergoing a major conformational change that is triggered by interactions with the target cell. The specific trigger depends on the virus.

Crossing the Cell Membrane Without Viruses May 14, 2025 ... (LNPs) for delivery to the cells of interest. LNPs are less immunogenic and less expensive to manufacure than viruses. ...

Special virus proteins, called "matrix" proteins, come together to form a lattice against the inside of the cell membrane. Matrix proteins are the drivers of the virus assembly process.

When we look at the way the virus acquires its membrane, a number of drugs might be used to disrupt its pathway. This has been done before. Scientists working with tubercle bacilli in the 1950s ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or ...

An obscure group of phages offers insights into elements of microbial warfare—and blueprints for new antibiotics.

Were there already viruses on Earth when the first living cells appeared billions of years ago? – Aayush A., age 16, India ...

A new study reveals the biological secret to the Zika virus's infectious success: Zika uses host cells' own "self-care" system of clearing away useless molecules to suppress the host proteins that ...