AstraZeneca has received another boost to its aspirations in oncology with the FDA approval of Calquence, a next generation treatment for mantle cell lymphoma (MCL). Calquence (acalabrutinib) is ...

Calquence (acalabrutinib) is a brand-name oral tablet that’s prescribed for certain types of cancer in adults. As with other drugs, Calquence can cause side effects, such as low levels of blood ...

CALQUENCE plus venetoclax with obinutuzumab reduced the risk of disease progression or death by 58% versus standard of care in this setting. CALQUENCE plus venetoclax poised to become first all ...

Calquence may reactivate the hepatitis B virus in people who already have this virus in their bodies. With reactivation, the virus becomes active again and causes symptoms.

Calquence is taken twice a day, about 12 hours between each dose, with or without food. Calquence comes in tablets and capsules. Do not open, crush, chew, or break the tablets and capsules.

AstraZeneca AZN announced that the FDA has accepted the supplemental new drug application (sNDA), seeking approval for the expanded use of Calquence (acalabrutinib) in mantle cell lymphoma (MCL).

Calquence, which was approved in the U.S. for chronic lymphocytic leukemia patients in November, was the only product of Acerta, which was acquired by AstraZeneca in a $7 billion deal in 2016.

Covid-19 patients who were on supplemental oxygen did better with Calquence than those on ventilators, the study showed. After being treated with Calquence for 10 to 14 days, 9 out of 11, or 82% ...

The ECHO trial enrolled during the pandemic, and a pre-specified analysis censoring for COVID-19-related deaths was conducted. Calquence combination regimen reduced the risk of disease progression ...

Calquence and Brukinsa were compared with Imbruvica in patients with relapsed/refractory CLL in the phase 3 ELEVATE-RR and ALPINE trials, respectively. However, differences in enrollment prevent ...

Calquence (acalabrutinib) has potential interactions with other medications and some supplements. For example, Calquence can interact with ketoconazole and carbamazepine. Calquence is a ...