Marcus Smith’s drop goal with the last kick of the fourth-round game last March delivered a 23-22 England win and derailed Ireland’s attempts to secure back-to-back Grand Slams.

Jamie George, replaced as England captain by Maro Itoje last week, has been ruled out of their Six Nations opener against Ireland, with scrumhalf Alex Mitchell also a doubt after the squad was hit by a raft of injuries.

Steve Borthwick has been forced into a drastic reshuffle of his Six Nations squad after Jamie George was ruled out of the opening two rounds, the former captain among four players to withdraw from the England squad.

England head coach Steve Borthwick has been forced to call up five players after his Six Nations squad was rocked by injury on a damaging weekend of club rugby.

First-choice scrum-half Alex Mitchell, who missed the autumn Tests with a neck injury, could also miss the game with a knee problem he picked up against Munster on Friday

England have suffered significant injury news ahead of the Six Nations with Jamie George set to miss their opening fixture against Ireland. Hooker George, who has been replaced by Maro Itoje as captain,