For example, there are strong theoretical arguments that a high mutation rate can only be sustained if each deleterious allele significantly reduces fitness, and yet the cumulative load due to ...

Panelists discuss recent phase 3 trials introducing novel endocrine agents such as proteolysis-targeting chimeras (PROTACs) ...

OFFinder, enhances CRISPR-Cas9 predictions by factoring in genetic variations like SNPs and deletions. It provides more ...

NIH’s SMaHT Network will chart trillions of somatic mutations to reveal how our DNA changes over a lifetime. In a nutshell ...

Paraphase – a computational tool that accurately resolves and analyzes paralogous genes – unlocks the difficult-to-analyze ...

Investigators have unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute ...

For example, a butterfly may produce offspring with new mutations. The majority of these mutations will have no effect; but one might change the color of one of the butterfly's offspring, making ...

Mismatch repair germline alterations occur frequently in uveal melanoma, suggesting it could be part of the Lynch syndrome spectrum.

Graveel, C. et al. Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele. Proc. Natl Acad. Sci. USA 101, 17198–17203 (2004).

Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.