The American Association for Cancer Research’s annual conference continued Tuesday with Marengo Therapeutics making progress ...

Replimune Group, Inc.'s RP1 + OPDIVO for advanced melanoma gains FDA Priority Review. PDUFA date: July 22, 2025. Read more on ...

Panelists discuss how chronic graft-vs-host disease (cGVHD) results from complex biological mechanisms involving inflammation, loss of peripheral tolerance, and fibrotic pathways affecting multiple ...

While mRNA vaccines represent a transformative platform for infectious disease control, their efficacy in antigen-presenting cells (APCs) remains vulnerable to endogenous regulatory networks, ...

Discover a study where researchers have discovered a myeloid-derived antigen-presenting cells population essential for peripherally induced regulatory T cells.

Reference: “Prdm16-dependent antigen-presenting cells induce tolerance to gut antigens” by Liuhui Fu, Rabi Upadhyay, Maria Pokrovskii, Francis M. Chen, Gabriela Romero-Meza, Adam Griesemer and Dan R.

Once inside the lymph node, the amphiphile lets go of albumin, allowing the drug to be taken up by antigen-presenting cells (APC), which stimulate a tumor-targeting T-cell response. The company ...

As an alternative to the conventional approach of accessing native APCs and using them to ... Acellular artificial antigen-presenting cells (aAPCs) are micro- or nano-particle-based reductionist ...

cytoplasmic entry into antigen-presenting cells (APCs), APC activation and endoplasmic reticulum targeting,” said Wang Ji, a researcher with the Institute of Precision Medicine at the First ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...