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Rates of proven drug hypersensitivity reactions are comparable between children with and without inborn errors of immunity (IEI).

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You may be prescribed broader-spectrum or second-line antibiotics that are less effective against certain infections, are more toxic and are associated with more adverse drug reactions.

In contrast, a true penicillin allergy involves your immune system and typically shows up within minutes to an hour of taking the medication. These reactions can include itchy hives or welts ...

Amoxicillin may cause mild side effects, including stomach issues, headaches, and yeast infections. Less commonly, people may have more severe reactions like seizures. Amoxicillin is a penicillin ...

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If you have symptoms from taking antibiotics such as an allergic reaction, you should talk to your doctor. Tightness in the throat, swelling, and having a hard time breathing are signs of anaphylaxis.

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Please share your thoughts and knowledge D.W. It isn’t always easy to tell whether a rash from an antibiotic, particularly a penicillin-type antibiotic, is a serious allergic reaction.

If the decision is made to try giving the antibiotic, it should be an explicit decision made and performed when resources are available to handle a serious allergic reaction if it occurs.