Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Two novel agents targeting angiopoietin-like protein 3 demonstrated safety and lipid-lowering capabilities in phase 2 trials, ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The specific location of each atom ...

Obesity and related metabolic disorders, such as hyperlipidemia and non-alcoholic fatty liver disease, have become ...

Scientists have developed an innovative technique that combines expansion microscopy with mass spectrometry imaging to ...

Nearly 150 years ago, scientists began to imagine how information might flow through the brain based on the shapes of neurons ...

New research challenges the view that proteins are the only key to evolution, highlighting the importance of lipids.

One promising technique – mass spectrometry imaging – overcomes some of these challenges. It allows researchers to see ...

For biologists, seeing is believing. But sometimes biologists have a hard time seeing. One particularly vexing challenge is ...

Small molecules are low molecular weight molecules that include lipids, monosaccharides ... into the molecular mechanisms that govern biological rhythms and enables control of immune pathways.