An Israeli study has identified TRIM63 as a significant genetic contributor to hypertrophic cardiomyopathy (HCM)—the most ...

When heart muscle gets damaged, the result is often permanent. Unlike other muscles in the body, the heart has long been ...

After earning a dual MD–PhD from the University of Maryland, Porter used his background in muscle cell biology to investigate heart development at Yale. It wasn’t until his move to Rochester, however, ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Potential side effects include bloating or diarrhea, weight gain related to water retention in muscle cells, and muscle cramps, says Kenneth Koncilja, M.D., a geriatrician at Cleveland Clinic. “The ...

This important study explored a molecular comparison of smooth muscle and neighboring fibroblast cells found in lung blood vessels afflicted by a disease called pulmonary arterial hypertension. In ...

This file photo taken at the University of Osaka in Suita, Osaka Prefecture, in January 2024, shows a cardiac muscle sheet made from iPS cells. (Kyodo) OSAKA (Kyodo) -- A startup in Tokyo on ...

It has been shown that the regulation of the extracellular matrix via cardiac fibroblasts plays a major role in ... of proinflammatory genes through endothelin in vascular smooth muscle cells (VSMCs).

causing first physiologic then pathologic cardiac hypertrophy 10,12. Prolongation of functional regeneration in senescent MLC/mIgf-1 muscle also reflects increased satellite cell proliferative ...

Department of Endocrinology, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life ...

“The water that gets pulled into the muscle cell, which creates the growth, also causes an immediate swelling,” Miranda says. (That’s why you might feel like your muscles are extra plump ...