Researchers have resolved the high-resolution structure of the human dopamine transporter bound to cocaine, providing critical insights into the molecular basis of cocaine's addictive properties.

Enzyme structure holds key to cocaine, heroin metabolism Implications for treatment, defense against chemical weapons Peer-Reviewed Publication ...

Chronic exposure to cocaine reduces the expression of a protein known to regulate brain plasticity, according to new, in vivo research on the molecular basis of cocaine addiction. That reduction ...

Scientists have long known that cocaine works by latching on to molecular connectors on the surface of brain cells, allowing dopamine, a chemical that promotes feelings of pleasure and reward, to ...

The structure of a bacterial cocaine esterase provides important new insight into the selectivity of the carboxylesterase enzyme family and the information gained from this work could lead to ...

Protein structure; Gluten; ... Molecular Fingerprint Of Cocaine Addiction Revealed. ScienceDaily. Retrieved May 8, 2025 from www.sciencedaily.com / releases / 2008 / 05 / 080527113200.htm.

In 2017, the U.S. Department of State revealed that American cocaine use and availability was on the rise for the first time in nearly a decade. It was bad news for public health officials, who ...

Now scientists say they have found a molecular connector, known as the BASP1 receptor, that binds cocaine, even when the drug is present in very low doses. Skip to main content Your source for the ...

In a recent study published in the journal Nature, researchers presented the molecular structure of dopamine transporter (DAT) complexed with cocaine. Cocaine is highly addictive, and its misuse ...