In a nutshell Scientists discovered that changing stem cells’ energy source from glucose to galactose creates “super stem ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...

Hepatocellular carcinoma (HCC) represents the most prevalent malignancy in Egypt and globally. However, non-invasive diagnostic/prognostic biomarkers for early detection of HCC are still lacking.

Engineers and biologists at Dartmouth College have found that, just like word order affects meaning in a sentence, the ...

Through the citrullination of histones, these enzymes facilitate chromatin relaxation, enabling access for RNA polymerase II and transcriptional machinery to initiate gene expression. On the other ...

The firm offers DecisionDx-Melanoma, a proprietary multi-gene expression profile (GEP) test that predicts the risk of metastasis and recurrence for patients diagnosed with invasive cutaneous melanoma.

A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, ...

Single cell techniques have revolutionized molecular life sciences. Ari Pekka Mähönen’s research group used single cell RNA sequencing to generate high resolution gene expression map of Arabidopsis ...

Bacteria can change the order of genes on their chromosome (the chromosome structure) and/or the three-dimensional arrangement of the chromosome (the chromosome conformation), altering gene expression ...

In this paper, a novel community detection method called MPSO-CD was proposed based on multi-objective particle swarm optimization, in which negative ratio association and ... MPSO-CD is applied to ...

By inserting an entire gene, the tool offers a one-and-done approach that overcomes hurdles from CRISPR gene editing technology—which is programmed to correct individual mutations—offering a ...