Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Golf Digest has published America’s 100 Greatest Golf Courses since 1966, making it the oldest and most respected ranking in ...

There’s something magical about walking into a Chicago institution where the wood paneling has absorbed decades of conversations and the aroma of perfectly seared beef hangs in the air like the ...

Complex traits are influenced by genes and the environment, but especially the latter is difficult to pin down. This important study uses C. elegans to demonstrate that non-genetic differences in gene ...

Now, scientists have the tools to map the actual battleground—the body—to see how gene expression changes as immune cells move through tissues and encounter other cells and health threats.

a technique to study gene expression in individual cells, to map the emergence of different cell types during the brain's development. Their findings, published in Nature Neuroscience, unveil gene ...

Although they've followed very different career paths over the past four decades, founding Kiss stars Gene Simmons and Ace Frehley have used remarkably similar set list formulas on their recent ...

A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...