A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, self-amplifying bursts that can damage nerve cells.

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

NEW YORK CITY, NEW YORK / ACCESS Newswire / April 22, 2025 /Neurovation Labs, Inc., a precision neuroscience biotechnology ...

Sea's molecules act as selective dual AMPAR (AMPA receptor), KAINR (kainate receptor) antagonists (DAKAs). DAKAs dampen the activity of the excitatory neurotransmitter glutamate which plays an ...

Sea's molecules act as selective dual AMPAR (AMPA receptor), KAINR (kainate receptor) antagonists (DAKAs). DAKAs dampen the activity of the excitatory neurotransmitter glutamate which plays an ...

Illustration of an AMPA receptor and glutamate. Credit: Edward Twomey, Johns Hopkins Medicine Scientists used advanced cryo-EM imaging to reveal how glutamate activates brain receptors, paving the way ...

Glutamate excites neurons, creating the electrical activity essential for normal brain function. This excitatory transmission occurs through several specialized receptors, including NMDA ...

Summary: Researchers used advanced cryo-electron microscopy to capture atomic-level images of how glutamate, a key neurotransmitter, opens channels in brain cells. These channels, known as AMPA ...

Its landing place on neurons is a channel called an AMPA receptor, which interacts with glutamate, and then acts like a pore that takes in charged particles. The ebb and flow of charged particles ...