Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint ...

Amgen is planning to push its olpasiran candidate for reducing lipoprotein(a) into phase 3 as quickly as possible as it tries to catch up with rival programmes at Novartis.

Antibodies against the hemagglutinin stalk confer protection in animal studies4-6. However, no data exist on natural infections in humans, and these antibodies do not show activity in the ...

Several studies have shown that experimental measurements of anti-HA antibody immunity (e.g., hemagglutination-inhibition or neutralization assays) can partially explain the evolutionary competition ...

In target-based drug discovery, quantification of target engagement is required to build structure–activity relationships and develop a potent clinical candidate. Target engagement data also provides ...

When asked about their preferred assay, 45% preferred using both assays, 33% preferred OSA alone, and 22% preferred CSA alone. Most (56%) providers did not routinely use BAT scores when screening ...

2.13 Hemagglutination inhibition assay. Serum samples were serially diluted 2-fold and incubated with 4 HA units of A/17/California/2009/38 (H1N1) virus (Changchun BCHT, Jilin, China) for 1 h at 37°C.

In vitro acetylcholinesterase inhibition assay - In this work, 27 crude methanol plant extracts were examined for their AChE inhibitory activities at concentrations of 1000, 100, and 10 mg/l and were ...