Mitochondria have primarily been known as the energy-producing components of cells. But scientists are increasingly ...

ROSWELL, Ga. and DUBLIN and HAMILTON, Bermuda, June 19, 2025 /PRNewswire/ -- Saol Therapeutics, a privately held, clinical-stage pharmaceutical company, today announced the presentation of key ...

Poorly energized mitochondria trap a subpopulation of mitochondrial precursor proteins in the intermembrane space. This article introduces ‘mitochondrial triage of precursor proteins’ (MitoTraP) as a ...

The interaction of Mia40 with Erv1/ALR is central to the oxidative protein folding in the intermembrane space of mitochondria (IMS) as Erv1/ALR oxidizes reduced Mia40 to restore its functional state.

“Until a few years ago, we were sure that mitochondria produced ATP via oxidative phosphorylation in the intermembrane space, where the inner and outer membranes interact. This has changed. We’ve ...

“Knowledge evolves, and what we present to students should also evolve,” Kowaltowski said. “Until a few years ago, we were sure that mitochondria produced ATP via oxidative phosphorylation in the ...

Mitochondria are double-membrane-enclosed organelles, containing an outer and inner membrane separated by an intermembrane space (Fig. 1). The function of mitochondria goes far beyond just ...

Inner membrane: The inner membrane is an ion-impermeable membrane that folds to form cristae in the interior of the mitochondrion. Intermembrane space: The intermembrane space is the sub-compartment ...

RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease Date: April 25, 2024 Source: Johannes Gutenberg Universitaet Mainz Summary: A team of ...

The modern mitochondria consists of a double membrane system with the inner and outer mitochondrial membranes separated by an intermembrane space. The inner mitochondrial membrane is a thick, gel-like ...