An engineered protein turns off the kind of immune cells most likely to damage tissue as part of type-1 diabetes, hepatitis, ...

Mortality and economic contraction during the 1918-1920 Great Influenza Pandemic provide plausible upper bounds for outcomes under the coronavirus (COVID-19). Data for 48 countries imply flu-related ...

Goldman Sachs 46th Annual Global Healthcare Conference June 11, 2025 2:00 PM ETCompany ParticipantsJames Patrick Kelly ...

While considerable emphasis has been placed on the S protein, numerous other proteins of SARS-CoV-2, such as N protein, also hold pivotal significance in viral physiology. However, our understanding ...

As a small tetrameric helical membrane protein, the M2 proton channel structure is highly sensitive to its environment. As a result, structural data from a lipid bilayer environment have proven to be ...

The design of the SARS-CoV-2 antigen used in the MVC-COV1901 vaccine involves a range of molecular modifications to the S-2P pre-fusion spike protein, a furitin cleavage site mutation, and T4 fibritin ...

Our SAXS findings imply that SARS-CoV-2 proteins may directly interact with lipid membranes, bypassing the need for the angiotensin-converting ... P. M. Thermoplasmonic Vesicle Fusion Reveals Membrane ...

The team compared original zinc finger proteins to the versions with AI-suggested mutations by evaluating both computer-based predictions and lab-based tests to confirm their performance improvement.

First-in-human study of AWT020, a bifunctional anti-PD-1/IL-2 fusion protein, in patients with advanced cancer. Ganessan Kichenadasse, Mark Voskoboynik, Sophia Frentzas, Xiaoli Cheng, Eugene Liu, ...

IBI363 is a first-in-class PD-1/IL-2 α-bias bispecific antibody fusion protein independently developed by Innovent Biologics. It functions by both blocking the PD-1/PD-L1 pathway and activating ...