Expression of proteins regulating mitochondrial biogenesis and content. Credit: Journal of Cachexia, Sarcopenia and Muscle (2025). DOI: 10.1002/jcsm.13763 ...

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes. Some of these conditions result from ...

Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes. Journal of Cachexia, Sarcopenia and Muscle , 2025; 16 (2 ...

Mitochondrial enzymatic activity and mtDNA density measures display low between-tissue correlations across 22 tissues from 27 mice. A long-standing assumption is that mitochondrial energy capacity ...

People often refer to mitochondria as the powerhouses of the cell. Their main function is to generate the energy necessary to power cells, but they are also involved in cell signaling and death.