A CRISPR/Cas9-based galactose screening identifies key mitochondrial genes involved in OXPHOS and oxidative metabolism, ...

State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China ...

Given that the fetal liver is primarily responsible for blood cell production, the researchers examined the liver cells of the affected fetuses, discovering that the formation of mitochondrial ...

However, it remains unknown whether impaired mitochondrial protein synthesis causes hematological disorders. The OXPHOS complexes normally incorporate various forms of iron into their structures ...

Mechanistic studies revealed that the mito-condition medium activates the AMPK pathway, a crucial cellular energy sensor, driving upregulation of mitochondrial biogenesis genes such as TFAM.

Cholesterol is critical for mitochondrial membrane structure and function. Given the emergence of mitochondria as a key factor in the pathogenesis of heart failure, mitochondrial cholesterol ...

3B,C). This observation is specially intriguing considering the report that the biogenesis of many mitochondrial proteins is enhanced upon overexpression of Tom70 (Liu et al, 2022). We can speculate ...

Researchers used gene knockdown and overexpression in kidney cells, along with biochemical assays to measure mitochondrial activity, NAD⁺ levels, and protein interactions related to PPDPF function.

The mitochondria act as the energy factories of our cells, creating ATP that drives our bodily functions. Inefficiencies in mitochondrial function have been associated with a variety of health ...

Scientists have revealed the assembly of the first brain mitochondria map, which they say could mark a significant first step toward unraveling age-related brain disorders. Mitochondria generate the ...

Additionally, the 20 mg of PQQ in each capsule supports mitochondrial biogenesis, which is essential for energy production in the body. While we have not experienced any negative side effects from ...