The project also shows that mammoths in the Modern Late Pleistocene fell into three genetic groups, all of which shared a most recent common ancestor around 780,000 years ago. Notably, this loosely ...

The study tracks mammoth evolution over a million years using mitogenomes, showing shifts in diversity and lineage tied to ...

Chronic fatigue, brain fog, and lack of drive are symptoms of a deeper physiological issue many have yet to identify: mitochondrial dysfunction. Mitochondria, often called the "powerhouses" of the ...

The study, published in Nature, shows that the compound, PZL-A, can improve mitochondrial DNA replication and energy production in patient-derived cells. Understanding POLG disorders and the need for ...

Get Instant Summarized Text (Gist) A deficiency in mitochondrial protein synthesis, due to the knockout of the MTO1 gene in hematopoietic cells, disrupts intracellular iron distribution, leading ...

TACOMA, Wash., April 08, 2025 (GLOBE NEWSWIRE) -- For years, I’d been searching for something—anything—that could give me real, lasting energy without the inevitable crash. I tried ...

Get Instant Summarized Text (Gist) A novel regulator of the mitochondrial sodium-calcium exchanger (NCLX), a protein called TMEM65, has been identified. TMEM65 aids in calcium removal from ...

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria ...

However, sometimes the DNA within parts of the cell known as mitochondria becomes damaged, which can lead to serious diseases. Professor Pla-Martín from the Institute of Biochemistry and Molecular ...

The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ejected ...