If mouse models of human disease are used incautiously, the best-laid plans of researchers might also, as the poet said, go awry. Researchers, however, may avoid coming to grief if they heed ...

“The mouse genome represents a very important chapter in evolution’s lab notebook. Being able to read this notebook and compare genomic information across species allows us to glean important ...

Ansari-Lari, M.A. et al.Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.

Figure 1: Gene structure and alternative splicing of human–mouse ortholog pairs. A strong divergence emerges, however, when we compare conservation of alternatively spliced exons (Fig. 3 ...

Scientists at The Jackson Laboratory (JAX) have developed mouse models that survive premature death and enable pre-clinical ...

Mice -- cheap to breed and handle in labs, and not presenting the same level of ethical concerns as research with non-human primates such as chimpanzees -- are one of the most commonly used models ...

Parts of human, mouse, chicken, dog, and even fish DNA called ultra-conserved elements haven’t tolerated a single change in the last 80 million years May 23, 2025 e-Paper LOGIN Account ...

But the research topic is, for obvious reasons, controversial. Scientists have largely steered clear of trying to create full ...

The Synthetic Human Genome, or Syn HG, a project launched on June 26th, aims to change that. Funded partly by Wellcome, a ...

As if sequencing a full human genome wasn't tricky enough, scientists are now attempting to reconstruct our species' genetic ...

Putting the uniquely human version of a certain gene into mice changed the way that those animals vocalized to each other, suggesting that this gene may play a role in speech and language.