The enclosure is designed to prevent casual removal of the media. To Disk Utility, it identifies as PCI-E storage. Nekteck is properly identified as the vendor in the macOS System Report.

Both of the enclosures attach directly to the USB 3.0 port of your computer and support a single HDD inside. The S35 can work with HDDs up to 1TB or more in capacity, as can the S25.