A human self-organizing 2D neuromuscular junction model. Immunofluorescence analysis of the whole dish shows muscle cells (magenta) organized in bundles surrounded by spinal cord neurons (cyan ...

Alessia Urzi et al. (2023): “Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells”, Nature Communications, DOI: 10.1038/s41467-023-43781-3 .

The model contains neurons, muscle cells, and the chemical synapse named neuromuscular junction that is needed for the two types of cells to interact. The researchers have now published their ...

Curi Bio, Genetox, and DreamCIS Sign MOU for Strategic Collaboration on 3D Neuromuscular Junction Model for Botox Potency Assay. Business Wire . Thu, Feb 22, 2024, 12:00 PM 5 min read.

The effects of VCA-894A were confirmed in Hesperos' Human-on-a-Chip ® neuromuscular junction model with patient-derived cells where VCA-894A demonstrated significant improvements in neuromuscular ...

New method allows for realistic, 3D model of the neuromuscular junction. Jan 6, 2022. Skeletal muscle grown in a dish offers insight into neuromuscular diseases. Sep 17, 2021.

Results from the MPS disease model indicated a significant reduction in the number of functional neuromuscular junctions (NMJ’s), stability of those NMJ’s that did form, and an increased ...

Company presented clinical and preclinical data at the MDA Conference last week in Dallas, Texas Oral presentation included data from MuSK-MG rat model depicting increases in muscle function and ...

Neuromuscular disorders may affect the peripheral nerves, skeletal muscles, or neuromuscular junction (where the nerves and muscles meet). Common neuromuscular disorders.