Fig 4. OS in chemotherapy-treated versus no chemotherapy–treated NC. NC, nuclear protein in testis carcinoma; OS, overall survival. Furthermore, the prevalence of NC was assessed in comparison with ...

Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database We analyzed the genomic and immune ...

Kapitein and colleagues noted that huntingtin aggregates inside the nucleus disrupt the protein meshwork that underlies and strengthens the nuclear envelope, making the membrane more likely to ...

Each had an average of 30-fold more of the insoluble RNA-binding proteins in nuclei than did age- and sex-matched controls (image below). Going Nuclear. In cortical tissue from healthy people (top), ...

The numerous cells that make up mammalian tissues are surrounded by an intricate network of proteins known as the extracellular matrix (ECM). Together, these proteins provide cells with a structural ...

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type ...

25,34,37,38 Pentraxins also bind to phospholipids and small nuclear ribonucleoproteins ... Extracellular matrix proteins, including fibrinogen and fibronectin, bind microbes and facilitate their ...

what is then left is a fibrous meshwork of proteins called the nuclear matrix. This is like a building from which all movables have been sucked out, leaving only the beams, ceiling, walls ...

The CNIC scientists have now shown that the YAP shuttle protein partner is importin-7, which binds YAP and transports it to the nucleus, where it can induce cell and tissue growth.

A research group at the University of Basel has now shown that different shuttle proteins occupy the nuclear pore to prevent unsolicited leakage of molecules. These proteins form an escape-proof, ...

However, the antagonistic mechanisms against antiviral innate immunity by accessory proteins differ among viruses. Here, we summarize the current understandings of immune evasion mechanisms by ...