Organelle biogenesis is the biological process by which cells establish, maintain, and propagate their membrane-bound compartments, including their specific protein and lipid compositions, morphology, ...

Peroxisomes are dynamic, membrane‐bound organelles crucial for lipid metabolism, reactive oxygen species detoxification and cellular redox homeostasis. Their biogenesis involves a dual mode of ...

An international team led by researchers at The Hospital for Sick Children (SickKids), Princess Margaret Cancer Centre, Dalhousie University, the University of Exeter (UK) and the Medical University ...

Researchers at the University of Virginia (UVA) School of Medicine have uncovered a potential path to treatment for persistent COVID-19 symptoms impacting the lungs. The work, published in Science in ...

Figure. Targeting DEPP1 to restore organelles as a therapy for ischemic cardiomyopathy. Myocardial infarction induces development of ischemic cardiomyopathy via multiple mechanisms and Wyant et al ...

Rationale: Peroxisome proliferator-activated receptors (PPARs) (α, γ, and δ/β) are nuclear hormone receptors and ligand-activated transcription factors that serve as key determinants of myocardial ...

Zellweger syndrome is a rare genetic disorder that causes very serious health problems shortly after birth. Newborns usually develop problems with their brain, liver, and kidneys. Zellweger syndrome, ...

The peroxisomal compartment comprises an important part of eukaryotic cells. Once neglected, in the recent decades it has gained increasing attention, which has resulted in accumulation of tremendous ...

SAN DIEGO--(BUSINESS WIRE)--In a joint effort to provide lower cost and more defined reagents and media to the cell and gene therapy market, Nucleus Biologics, The Cell Performance Company™, a leading ...

ABSTRACT: Growth rate of Yarrowia lipolytica NCIM 3589 was observed in a fermentation medium consisting of peptone, yeast extract, sodium chloride. Logistic equation was fitted to the growth data ...

The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins ...