The ensemble of skeletal muscles can be considered the largest metabolic and endocrine organ of the human body. The more than ...

Widespread neuronal mitochondrial complex I (CI) deficiency was recently reported to be a characteristic in a subgroup of individuals with idiopathic Parkinson's disease (PD). Here, we sought to ...

Musculoskeletal health ensures mobility and strength. Learn exercise, diet, and posture tips to protect bones, muscles, and ...

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting ...

Imagine suddenly losing the ability to move a limb, walk or speak. You would probably recognize this as a medical emergency ...

An interdisciplinary research team led by Professor Dr. Bent Brachvogel has examined how mitochondria influence the premature ...

A Nature Metabolism study shows that, under acute stress, fatty acids liberated by lipolysis of white fat cells cause release from local macrophages of the growth-differentiation factor GDF15 ...

When a patient develops systemic mastocytosis in adulthood, the disorder is typically ... classification system, mastocytosis can be divided into cutaneous mastocytosis and SM. There are 5 subtypes of ...

SHENZHEN, April 7 (Xinhua) -- Chinese scientists have, for the first time, confirmed the existence of microglia in the peripheral nervous system (PNS ... neurological diseases such as ...

Obesity and its associated metabolic disorders─including muscle atrophy─pose significant ... while promoting the phosphorylation of mTOR/AKT/p70S6K and FOXO3a in skeletal muscle. The FGF15/FGFR4/ERK ...