Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's ...

Mechanistic discrepancies between species highlights the limitations of mouse models in advancing STING inhibition drugs for various diseases.

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's ...

Follicular thyroid cancer, which is 10% of cases: Generally grows slowly but can spread to distant sites. Medullary thyroid cancer, which is less than 5% of cases: Sometimes hereditary and more ...

Worldwide, the incidence of thyroid cancer is increasing, with 586 202 new cases diagnosed in 2020.1 In high-income countries, the majority of these cases are early-stage cancers detected mainly by ...

Standard of care cancer therapies are ineffective for many patients. While immunotherapies blocking the programmed cell death ligand 1 (PD-L1) have shown some improvement, >60% of patients are ...

Genes tied to inflammation were dialed down, while genes linked to healthy brain signaling and memory were turned up. In other words, blocking STING not only stopped damage—it helped restore ...

Paramount Global chair Shari Redstone has disclosed that she underwent surgery for thyroid cancer in May after being diagnosed earlier this year. A spokesperson for Redstone said, “Shari ...

Surgeons removed her thyroid gland but did not fully eradicate the cancer, which had spread to her vocal cords, the paper said. She continues to be treated with radiation, the paper reported.

Whole-cell cancer vaccines can trigger broader-spectrum antitumoral immune responses. However, a lack of immunogenicity and unclear interactions with antigen-presenting cells (APCs) hinder their ...