Scientists have uncovered the molecular pathways involved in the inhibition of protein synthesis in cells by aspirin, a discovery that may have implications for the treatment of cancer.

The best-characterized mechanism of action of aspirin occurs through permanent inactivation of the cyclooxygenase (COX) activity of prostaglandin H (PGH) synthase 1 and synthase 2, also referred ...

Aspirin was thus unable to prevent migration, invasion, and metastasis in miR-34-deficient cancer cells. It was already known that the miR-34 genes are induced by the transcription factor p53 and ...

Mechanism Behind Aspirin’s Protective Effect Against Colorectal Cancer Identified Aspirin can reduce colorectal cancer risk and inhibit cancer progression. A new study has shown how. News . Published: ...

The mechanism behind aspirin's anti-cancer effect. Aspirin works by inhibiting the production of thromboxane A2 (TXA2), a molecule produced by blood platelets.

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; ... New insights into the mechanisms of aspirin-exacerbated respiratory disease, ...

Aspirin could prevent some cancers from spreading, according to new research. Scientists uncovered the mechanism behind how ...

Colorectal cancer (bowel cancer) is the third most common form of cancer worldwide, with around 1.9 million newly diagnosed cases and 900,000 deaths every year. Therefore, preventive substances ...