Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Identification of a spliced leader RNA binding protein from Trypanosoma cruzi Mol Biochem Parasitol 112: 39-49. Yoshida N, Favoreto S Jr, Ferreira AT, Manque PM 2000. Signal transduction induced in ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

Intercellular fluid flow, not just cell structure, governs how tissues respond to physical forces by Jennifer Chu, Massachusetts Institute of Technology edited by Sadie Harley, reviewed by Robert Egan ...

β-Lactam antibiotics have long been a treatment of choice for bacterial infections since they bind irreversibly to Penicillin-Binding Proteins (PBPs), enzymes that are vital for cell wall biosynthesis ...

Trypanosoma cruzi and Trypanosoma rangeli -like trypanosomes have been found in a variety of neotropical bat species. In this study, bats (Artibeus lituratus, Carollia perspicillata, Desmodus rotundus ...

Rhodesain (RD) is a parasitic, human cathepsin L (hCatL) like cysteine protease produced by Trypanosoma brucei (T. b.) species and a potential drug target for the treatment of human African ...