From a meeting that celebrates basic research and being "first," a look at 3 data sets on therapies that would break new ...

Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to ...

Department of Pharmacology, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for ...

Yet, tumors disrupt this role by inducing structural remodeling—such as lymphangiogenesis, and recruiting immunosuppressive cells, including Tregs, Bregs, and immunosuppressive DC subtypes, creating a ...

The OB:OC 7:1 ratio was the most suitable to follow the remodeling activity. The 10× SBF collagen coating technique provides a biomimetic bone-like microenvironment on CCP, consisting of carbonated ...

The potential shock of tariff-related price hikes on everything from lumber to dishwashers would come at a time when Americans are spending more than ever on home remodeling—a trend that began ...

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...

Liver Cancer Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA; daniela.sia{at}mssm.edu Objective The diversity of the tumour microenvironment (TME) of intrahepatic ...