The administration recently announced a new payment model to align some Medicare Part B drug payments with international pricing benchmarks. Various factors could affect the model’s scope and impact.
A new pilot Medicaid program — GENEROUS — combines centralized pharmaceutical-coverage negotiations with most-favored-nation pricing in an effort to lower drug costs, but it has some limitations.
An 86-year-old man presented to the neurology clinic with 2 years of progressive memory loss and difficulty walking. An MRI showed microbleeds that appeared as hypointense foci throughout the ...
A 76-year-old woman, who had a history of treated hepatitis C virus infection, presented with rapidly progressive kidney failure and a stroke. Palpable purpura on the legs was noted. A diagnosis ...
The author describes the scientific foundations and implications of the results of a randomized, controlled trial of Mim8, a new mimetic of factor VIIIa, to treat hemophilia A.
In this trial of arthroscopic partial meniscectomy for degenerative medial meniscal tear in adults, participant-reported and radiologic outcomes over 10 years of follow-up suggested no benefit and ...
Guidelines recommend a trial of antiarrhythmic drugs before catheter ablation for persistent atrial fibrillation. Whether pulsed field ablation (PFA) may be a preferred initial treatment is ...
There has been substantial interest in the development of GLP-1 drugs and optimism about their public health effects. But some worrisome signals related to disordered eating have emerged.
Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three ...
The Pediatric Research Equity Act was intended to promote the development and testing of prescription drugs for children. But its implementation has been constrained.
A 27-year-old woman presented with a 2-week history of joint pain, fever, sore throat, and a nonpruritic rash that worsened during fever. Laboratory tests showed an elevated ESR and elevated ...