- Influenza virus nucleoprotein (NP) is a structural protein which encapsidates the negative strand viral RNA. NP is one of the main determinants of species specificity.Learn more:Influenza virus nucleoprotein (NP) is a structural protein which encapsidates the negative strand viral RNA. NP is one of the main determinants of species specificity.en.wikipedia.org/wiki/Influenza_virus_nucleoproteinThe genome of influenza A viruses consists of eight segments of single-stranded, negative-sense RNA that are encapsidated as individual rod-shaped ribonucleoprotein complexes (RNPs). Each RNP contains a viral RNA, a viral polymerase and multiple copies of the viral nucleoprotein (NP).www.sciencedirect.com/science/article/pii/S001457…Influenza virus nucleoprotein (NP) is the major structural protein which interacts with the 8 segment RNAs, to make the panhandle structure of RNPs, nucleocapsids, together with 3 polymerase protein complex (PB2, PB1, and PA).pubmed.ncbi.nlm.nih.gov/9360378/Influenza A virus nucleoprotein (NP) forms homo-oligomers and multiple copies of NP wrap around genomic RNA, along with a trimeric polymerase making up ribonucleoprotein (RNP) complex.pubmed.ncbi.nlm.nih.gov/19471866/
Cryo-EM structure of influenza helical nucleocapsid …
Dec 15, 2023 · In this study, we established a biological tool, the RNP-like particles assembled from recombinant influenza A virus NP and synthetic RNA, and we present the first subnanometric cryo–electron microscopy structure of …
Structure of Influenza Virus Ribonucleoprotein …
The genomes of influenza A and B viruses consist of eight single-stranded negative-sense RNA segments, while that of influenza C virus consists of seven RNA segments. Each viral RNA (vRNA) segment forms a ribonucleoprotein …
- Studies of NP Structure of Influenza Virus
Structure of the influenza virus A H5N1 nucleoprotein: …
Similar to other NSRVs, the genome of the influenza virus is encapsidated by NP. The primary function of NP is to condense the segmented genomic RNA into a …
- Bond angle (degrees): 1.236
- Bond length (Å): 0.009
Influenza A virus nucleoprotein: a highly conserved multi …
2. STRUCTURES OF INFLUENZA A VIRUS NP. The first X-ray crystal structure of NP to come to light was the A/WSN/33 (H1N1) NP structure (PDB: 2IQH) . This structure was solved without …
Influenza virus nucleoprotein - Wikipedia
Influenza virus nucleoprotein (NP) is a structural protein which encapsidates the negative strand viral RNA. NP is one of the main determinants of species specificity. The question of how far …
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Review Structure and assembly of the influenza A virus ...
Apr 17, 2013 · Influenza A viruses, the causative agents of both epidemic and pandemic flu, are enveloped, single-stranded, negative-sense RNA viruses [1]. The genome of the influenza A …
Crystal structures of influenza nucleoprotein complexed with …
Mar 30, 2021 · Here we present the crystal structure of an obligate monomer of H5N1 NP in complex with RNA nucleotides to 2.3 Å, and a C-terminal truncation of this mutant, also in …
Crystal structures of influenza nucleoprotein complexed with …
Apr 19, 2021 · Binding of RNA by NP is a crucial step for template re-encapsidation during transcription and replication and cRNP formation. Our structures thus provide insights into the …
[Structure and function of influenza virus nucleoprotein (NP)]
Influenza virus nucleoprotein (NP) is the major structural protein which interacts with the 8 segment RNAs, to make the panhandle structure of RNPs, nucleocapsids, together with 3 …
Structure of the influenza virus A H5N1 nucleoprotein ... - PubMed
The nucleoprotein (NP) of the virus binds the RNA genome and acts as a key adaptor between the virus and the host cell. It, therefore, plays an important structural and functional role and …
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